Publications

The innovative and cutting edge research conducted by Broad Stem Cell Research Center faculty has led to an impressive record of published articles in the most prestigious scientific peer reviewed journals, including Nature, Cell and Proceedings of the National Academy of Science (PNAS). The publications below represent a small selection of recent discoveries published by BSCRC faculty.

Human Developmental Chondrogenesis as a Basis for Engineering Chondrocytes from Pluripotent Stem Cells
Online December 12, 2013 - Stem Cell Reports
Ling Wu, Carolina Bluguermann, Levon Kyupelyan, Brooke Latour, Stephanie Gonzalez,
Saumya Shah, Zoran Galic, Sundi Ge, Yuhua Zhu, Frank A. Petrigliano, Ali Nsair, Santiago G. Miriuka, Xinmin Li, Karen M. Lyons, Gay M. Crooks, David R. McAllister, Ben Van Handel, John S. Adams, and Denis Evseenko

Low levels of circulating estrogen sensitize PTEN-null endometrial tumors to PARP inhibition in vivo
Online November 12, 2013 - Molecular Cancer Therapeutics
Deanna M. Janzen, Daniel Y. Paik, Miguel A. Rosales et al.

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
Online July 28, 2013 - Nature
Zhigang Xue, Kevin Huang, Chaochao Cai, Lingbo Cai, Chun-yan Jiang, Yun Feng, Zhenshan Liu, Qiao Zeng, Liming Cheng, Yi E. Sun, Jia-yin Liu, Steve Horvath, and Guoping Fan

β-globin gene transfer to human bone marrow for sickle cell disease
Online July 1, 2013 - Journal of Clinical Investigation
Zulema Romero, Fabrizia Urbinati, Sabine Geiger, Aaron R. Cooper, Jennifer Wherley, Michael L. Kaufman, Roger P. Hollis, Rafael Ruiz de Assin, Shantha Senadheera, Arineh Sahagian, Xiangyang Jin, Alyse Gellis, Xiaoyan Wang, David Gjertson, Satiro DeOliveira, Pamela Kempert, Sally Shupien, Hisham Abdel-Azim, Mark C. Walters, Herbert J. Meiselman, Rosalinda B. Wenby, Theresa Gruber, Victor Marder, Thomas D. Coates and Donald B. Kohn

Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy
Online June 6, 2013 - Cancer Research
D.M. Janzen, M.A. Rosales, D.Y. Paik, D.S. Lee, D.A. Smith, O.N. Witte, M.L. Iruela-Arispe, S. Memarzadeh

SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs
Online May 7, 2013 - Nature Communications
Peiyee Lee, Nathan T. Martin, Kotoka Nakamura, Soheila Azghadi, Mandana Amiri, Uri Ben-David, Susan Perlman, Richard A. Gatti, Hailiang Hu & William E. Lowry

A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria
Online April 15, 2013 - Developmental Cell
Deepa V. Dabir, Samuel A. Hasson, Kiyoko Setoguchi, Meghan E. Johnson, Piriya Wongkongkathep, Colin J. Douglas, Johannes Zimmerman, Robert Damoiseaux, Michael A. Teitell, Carla M. Koehler

Multifunctional T-cell Analyses to Study Response and Progression in Adoptive Cell Transfer Immunotherapy
Online March 21, 2013 - Cancer Discovery
Chao Ma, Ann F. Cheung, Thinle Chodon, Richard C. Koya, Zhongqi Wu, Charles Ng, Earl Avramis, Alistair J. Cochran, Owen N. Witte, David Baltimore, Bartosz Chmielowski, James S. Economou, Begonya Comin-Anduix, Antoni Ribas, and James R. Heath

Introduction of Exogenous T-cell Receptors Into Human Hematopoietic Progenitors Results in Exclusion of Endogenous T-cell Receptor Expression
Online March 12, 2013 - Nature
Dimitrios N. Vatakis, Balamurugan Arumugam, Sohn G. Kim, Gregory Bristol, Otto Yang, and Jerome A. Zack

Haemogenic endocardium contributes to transient definitive haematopoiesis
Published March 5, 2013 - Nature Communications
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Haruko Nakano, Xiaoqian Liu, Armin Arshi, Yasuhiro Nakashima, Ben van Handel, Rajkumar Sasidharan, Andrew W. Harmon, Jae-Ho Shin, Robert J. Schwartz, Simon J. Conway, Richard P. Harvey, Mohammad Pashmforoush, Hanna K. A. Mikkola, & Atsushi Nakano

Perivascular support of human hematopoietic cells
Pre-published Online February 14, 2013 - Blood Journal
Mirko Corselli, Chee Jia Chin, Chintan Parekh, Arineh Sahaghian, Wenyuan Wang, Shundi Ge, Denis Evseenko, Xiaoyan Wang, Elisa Montelatici, Lorenza Lazzari, Gay M. Crooks, Bruno Péault

Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells
Online February 14, 2013 - Cell Stem Cell
John J. Vincent, Yun Huang, Pao-Yang Chen, Suhua Feng, Joseph H. Calvopiña, Kevin Nee, Serena A. Lee, Thuc Le, Alexander J. Yoon, Kym Faull, Guoping Fan, Anjana Rao, Steven E. Jacobsen, Matteo Pellegrini, Amander T. Clark

Human Perivascular Stem Cells Show Enhanced Osteogenesis and Vasculogenesis with NELL-1 Protein
Online February 13, 2013 - Tissue Eng Part A
Askarinam A, James AW, Zara JN, Goyal R, Corselli M, Pan A, Liang P, Chang L, Rackohn T, Stoker D, Zhang X, Ting K, Péault B, Soo C.

Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells
Online February 5, 2013 - Molecular Therapy
Francesca Giannoni, Cinnamon L Hardee, Jennifer Wherley, Eric Gschweng, Shantha Senadheera, Michael L Kaufman, Rebecca Chan, Ingrid Bahner, Vivian Gersuk, Xiaoyan Wang, David Gjertson, David Baltimore, Owen N Witte, James S Economou, Antoni Ribas and Donald B Kohn

Small Molecule Screening with Laser Cytometry Can Be Used to Identify Pro-Survival Molecules in Human Embryonic Stem Cells
Online January 2013 - PLoS One
Sean P. Sherman, April D. Pyle

Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene
Pre-published Online January 14, 2013 - PNAS
Melissa N. McCracken, Eric H. Gschweng, Evan Nair-Gill, Jami McLaughlin, Aaron R. Cooper, Mireille Riedinger, Donghui Cheng, Christopher Nosala, Donald B. Kohn, and Owen N. Witte

Expansion on Stromal Cells Preserves the Undifferentiated State of Human Hematopoietic Stem Cells Despite Compromised Reconstitution Ability
Online January 2013 - PLoS One
Mattias Magnusson, Maria I. Sierra, Rajkumar Sasidharan, Sacha L. Prashad,
Melissa Romero, Pamela Saarikoski, Ben Van Handel, Andy Huang, Xinmin Li,
Hanna K.A. Mikkola

The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation
Online December 2012 - Nature Cell biology
Sofia Gkountela, Ziwei Li, John J. Vincent, Kelvin X. Zhang, Angela Chen, Matteo Pellegrini & Amander T. Clark

Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy
Online December 2012 - Science Translational Medicine
Genevieve C. Kendall, Ekaterina I. Mokhonova, Miriana Moran, Natalia E. Sejbuk, Derek W. Wang, Oscar Silva, Richard T. Wang, Leonel Martinez, Qi L. Lu, Robert Damoiseaux, Melissa J. Spencer, Stanley F. Nelson and M. Carrie Miceli

Characterization and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells
Online October 2012 - PLoS One
Ali Nsair, Katja Schenke-Layland, Ben Van Handel, Dennis Evseenko, Michael Kahn, Peng Zhao, Joseph Mendelis, Sanaz Heydarkhan, Obina Awji, Miriam Vottler, Susanne Geist, Jennifer Chyu, Nuria Gago-Lopez, Gay M. Crooks, Kathrin Plath, Josh Goldhaber, Hanna K.A. Mikkola, W. Robb MacLellan

Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans
Online September 11, 2012 - Blood Journal
Fabio Candotti, Kit L. Shaw, Linda Muul, Denise Carbonaro, Robert Sokolic, Christopher Choi, Shepherd H. Schurman, Elizabeth Garabedian, Chimene Kesserwan, G. Jayashree Jagadeesh, Pei-Yu Fu, Eric Gschweng, Aaron Cooper, John F. Tisdale, Kenneth I. Weinberg, Gay M. Crooks, Neena Kapoor, Ami Shah, Hisham Abdel-Azim, Xiao-Jin Yu, Monika Smogorzewska, Alan S. Wayne, Howard M. Rosenblatt, Carla M. Davis, Celine Hanson, Radha G. Rishi, Xiaoyan Wang, David Gjertson, Otto O. Yang, Arumugam Balamurugan, Gerhard Bauer, Joanna A. Ireland, Barbara C. Engel1, Gregory M. Podsakoff, Michael S. Hershfield1, R. Michael Blaese, Robertson Parkman, and Donald B. Kohn

Lymphoid priming in human bone marrow begins before expression of CD10 with upregulation of L-selectin
Online September 2, 2012 - Nature Immunology
Lisa A Kohn, Qian-Lin Hao, Rajkumar Sasidharan, Chintan Parekh, Shundi Ge, Yuhua Zhu, Hanna Mikkola and Gay Crooks

Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium
Online August 2, 2012 - Cell
Ben Van Handel, Amelie Montel-Hagen, Rajkumar Sasidharan, Haruko Nakano, Roberto Ferrari, Cornelis J. Boogerd, Johann Schredelseker, Yanling Wang, Sean Hunter, Tonis Org, Jian Zhou, Xinmin Li, Matteo Pellegrini, Jau-Nian Chen, Stuart H. Orkin, Siavash K. Kurdistani, Slyvia M. Evans, Atsushi Nakano and Hanna Mikkola

Glucose Deprivation Activates a Metabolic and Signaling Amplification Loop Leading to Cell Death
Online June 26, 2012 - Molecular Systems Biology
Nicholas A. Graham, Martik Tahmasian, Bitika Kohli, Evangelia Komisopoulou, Maggie Zhu, Igor Vivanco, Michael A. Teitell, Hong Wu, Antoni Ribas, Roger S. Lo, Ingo K. Mellinghoff, Paul S. Mischel and Thomas G. Graeber

Perivascular Stem Cells: A Prospectively Purified Mesenchymal Stem Cell Population for Bone Tissue Engineering
Online June 11, 2012 - Stem Cells Translational Medicine
Aaron W. James, Janette N. Zara, Xinli Zhang, Asal Askarinam, Raghav Goyal, Michael Chiang, Wei Yuan, Le Chang, Mirko Corselli, Jia Shen, Shen Pang, David Stoker, Ben Wu, Kang Ting, Bruno Péault, and Chia Soo

Functional Neuromuscular Junctions Formed by Embryonic Stem Cell-Derived Motor Neurons
May 4, 2012 - PLoS ONE
Joy A. Umbach, Katrina L. Adams, Cameron B. Gundersen, Bennett G. Novitch

Foxp-Mediated Suppression of N-Cadherin Regulates Neuroepithelial Character and Progenitor Maintenance in the CNS
April 25, 2012 - Neuron
David L. Rousso, Caroline Alayne Pearson, Zachary B. Garber, Amaya Miquelajauregui, Shanru Li, Carlos Portera-Cailliau, Edward E. Morrisey, Bennett G. Novitch

Risk and Reward in Stem Cell Products: A New Model for Stem Cell Product Liability
April 11, 2012 - Boston University Journal of Science and Technology Law
Stephen R. Munzer

Correcting human mitochondrial mutations with targeted RNA import
March 12, 2012 - PNAS Early Edition
Geng Wang, Eriko Shimada, Jin Zhang, Jason S. Hong, Geoffrey M. Smith, Michael A. Teitell and Carla M. Koehler

Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila
Published Online March 11, 2012 - Nature Cell Biology
Jiwon Shim, Tina Mukherjee, Utpal Banerjee

Trophoblasts Regulate the Placental Hematopoietic Niche through PDGF-B Signaling
March 13, 2012 - Developmental Cell 22, 651-659
Akanksha Chhabra, Andrew J. Lechner, Masaya Ueno, Asha Acharya, Ben Van Handel, Yanling Wang, M. Luisa Iruela-Arispe, Michelle D. Tallquist, and Hanna K.A. Mikkola

Interaction between Differentiating Cell- and Niche-Derived Signals in Hematopoietic Progenitor Maintenance
December 23, 2011 - Cell 147, 1589-1600
Bama Charan Mondal, Tina Mukherjee, Lolitika Mandal, Cory J. Evans, Sergey A. Sinenko, Julian A. Martinez-Agosto, and Utpal Banerjee

From Skin Biopsy to Neurons through a Pluripotent Intermediate Under Good Manufacturing Practice Protocols
Published Online December 7, 2011 - Stem Cells Translational Medicine 2012;1:36-43
Saravanan Karumbayaram, Peiyee Lee, Soheila F. Azghadi, Aaron R. Cooper, Michaela Patterson, Donald B. Kohn, April Pyle, Amander Clark, James Byrne, Jerome A. Zack, Kathrin Plath, William E. Lowry

Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin
Published Online November 30, 2011 - Human Molecular Genetics (2012) 21 (4): 751-764
Silvia V. Diaz Perez, Rachel Kim, Ziwei Li, Victor E. Marquez, Sanjeet Patel, Kathrin Plath, and Amander T. Clark

Antitumor Activity from Antigen-Specific CD8 T Cells Generated In Vivo from Genetically Engineered Human Hematopoietic Stem Cells
November 28, 2011 - PNAS, Published online before print
Dimitrios N. Vatakis, Richard C. Koya, Christopher C. Nixon, Liu Wei, Sohn G. Kim, Patricia Avancena, Gregory Bristol, David Baltimore, Donald B. Kohn, Antoni Ribas, Caius G. Radu Zoran Galic and Jerome A. Zack

UCP2 Regulates Energy Metabolism and Differentiation Potential of Human Pluripotent Stem Cells
October 14, 2011 - The EMBO Journal (2011), 1-14
Jin Zhang, Ivan Khvorostov, Jason S Hong, Yavuz Oktay, Laurent Vergnes, Esther Nuebel, Paulin N Wahjudi, Kiyoko Setoguchi, Geng Wang, Anna Do, Hea-Jin Jung, J Michael McCaffery, Irwin J Kurland, Karen Reue, Wai-Nang P Lee, Carla M Koehler, and Michael A Teitell

A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells
October 10, 2011 - Molecular Cancer Therapeutics 2011; 10:1818-1828
Koppany Visnyei, Hideyuki Onodera, Robert Damoiseaux, Kuniyasu Saigusa, Syuzanna Petrosyan, David De Vries, Denise Ferrari, Jonathan Saxe, Eduard H. Panosyan, Michael Masterman-Smith, Jack Mottahedeh, Kenneth A. Bradley, Jing Huang, Chiara Sabatti, Ichiro Nakano, Harley I. Kornblum

A Novel Stem/Progenitor Cell Population from Murine Tracheal Submucosal Gland Ducts with Multipotent Regenerative Potential

June 24, 2011 - Stem Cells, Accepted manuscript online
Ahmed E. Hegab, Vi Luan Ha, Jennifer L. Gilbert, Kelvin Xi Zhang, Stephen P. Malkoski, Andy T. Chon, Daphne O. Darmawan, Bharti Bisht, Aik T. Ooi, Matteo Pellegrini, Derek W. Nickerson, Brigitte N. Gomperts

Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx

April 19, 2011 - Developmental Cell, Volume 20, Issue 4, 419-429
Sangeeta Dhawan, Senta Georgia, Shuen-ing Tschen, Guoping Fan, and Anil Bhushan

Cardiac Origin of Smooth Muscle Cells in the Inflow Tract
February 2011 - Journal of Molecular and Cellular Cardiology, Volume 50, Issue 2, Pages 337-345
Haruko Nakano, Estrelania Williams, Masahiko Hoshijima, Mika Sasaki, Susumu Minamisawa, Kenneth R. Chien, Atsushi Nakano

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Mannes

January 7, 2011 - Cell Stem Cell 8, 59-71
Janel E. Le Belle, Nicolas M. Orozco, Andres A. Paucar, Jonathan P. Saxe, Jack Mottahedeh, April D. Pyle, Hong Wu, and Harley I. Kornblum

The first trimester human placenta is a site for terminal maturation of primitive erythroid cells
October 28, 2010 - Blood 116: 3321-3330
Van handel B, Prashad S, Hassenzadeh-Kiabi N, Huang A, Atanassova B, Magnusson M, Chen A, Hamalainen E, Mikkola HKA

Mechanistic Insights into Reprogramming to Induced Pluripotency
October 13, 2010 - Journal of Cellular Physiology 226(4): 868-78
Ritchie Ho, Constantinos Chronis, Kathrin Plath

Female human iPS cells retain an inactive X-chromosome
September 3 2010 - Cell Stem Cell 7(2): 329-342
Jason Tchieu, Edward Kuoy, Mark H. Chin, Hung Trinh, Michaela Patterson, Sean P. Sherman, Otaren Aimiuwu, Anne Lindgren, Shahrad Hakimian, Jerome A. Zack, Amander T. Clark, April D. Pyle, William E. Lowry, and Kathrin Plath

Molecular Analyses of Human Induced Pluripotent Stem Cells and Embryonic Stem Cells
August 6 2010 - Cell Stem Cell 7(2): 263-269
Chin MC, Pellegrini M, Plath K and Lowry WE

PNPASE Regulates RNA Import into Mitochondria
August 6 2010 - Cell 142(3):456-467
Wang, G., Chen, H.-C., Oktay, Y., Zhang, J., Allen, E.L., Smith, G.M., Fan, K.C., Hong, J.S., French, S.W., McCaffery, J.M., Lightowlers, R.N., Morse III, H.C., Koehler, C.M., and Teitell M.A.

Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells
August 3 2010 - PNAS 107(31):13742-7. [Epub ahead of print: 2010 Jul 19]
Evseenko D, Zhu Y, Schenke-Layland K, Kuo J, Latour B, Ge, S, Dravid G, Li X, MacLellan WR, Crooks GM.

Role of lipid metabolism in Smoothened de-repression in Hedgehog signaling
July 20 2010 - Developmental Cell 19(1):54-65
Yavari A, Nagaraj R, Owusu-Ansah E, Folick A, Ngo K, Hillman T, Call G, Rohatgi R, Scott M, Banerjee U.

Endothelial {alpha}3{beta}1-Integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF.
July 16 2010 - American Journal of Pathology
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA, Hodivala-Dilke KM.

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
July 2 2010 [Epub ahead of print] - nature biotechnology
Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, and Cannon PM.

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling
June 15 2010 - Developmental Cell 18(6):938-49
Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E.

Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions
May 7 2010 - Lab on a Chip 10(9):1113-9
Kamei K, Ohashi M, Gschweng E, Ho Q, Suh J, Tang J, For Yu ZT, Clark AT, Pyle AD, Teitell MA, Lee KB, Witte ON, Tseng HR.

Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
May 3, 2010 - Journal of Clinical Investigation 120(5):1494-505
Ahuja P, Zhao P, Angelis E, Ruan H, Korge P, Olson A, Wang Y, Jin ES, Jeffrey FM, Portman M, Maclellan WR.

chinmo is a functional effector of the JAK/STAT pathway that regulates eye development, tumor formation and stem cell self-renewal in Drosophila
April 20 2010 - Developmental Cell 18(4):556-568
Flaherty MS, Salis P, Evans CJ, Ekas LA, Marouf A, Zavadil J, Banerjee U, Bach EA.

Differential Sensitivity of Melanoma Cell Lines with BRAF V600E Mutation to the Specific BRAF Inhibitor PLX4032/RG7204
April 20 2010 - Journal of Translational Medicine 8 (1):39
Jonas N. Søndergaard, Ramin Nazarian, Qi Wang, Deliang Guo, Teli Hsueh, Stephen Mok, Hooman Sazegar, Laura E. MacConaill, Jordi G. Barretina, Sarah M. Kehoe, Narsis Attar, Jonathan E. Zuckerman, Bartosz Chmielowski, Begoña Comin-Anduix, Richard C. Koya, Paul S. Mischel, Roger S. Lo, Antoni Ribas.

Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes
April 15 2010 - Human Molecular Genetics 19 (8):1603-1617
Lee R, Chang S, Trinh H, Tu Y, White AC, Davies B, Bergo M, Fong L, Lowry WE and Young SG.

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
April 15 2010 - Nature 464(7291): 1067-70.
Mark E. Davis, Jonathan E. Zuckerman, Chung Hang J. Choi, David Seligson, Anthony Tolcher, Christopher A. Alabi, Yun Yen, Jeremy D. Heidel, Antoni Ribas.

Regulated Expansion of Human Pancreatic β-Cells
April 13 2010 - Molecular Therapy 18:1389-96
Pais E, Park J, Alexy T, Nikolian V, Ge S, Shaw K, Senadheera S, Hardee CL, Skelton D, Hollis R, Crooks GM and Kohn DB.

Imaging CTLA4 Blockade-induced Cell Replication with [18F]FLT PET in Patients with Advanced Melanoma Treated with Tremelimumab
March 2010 - Journal of Nuclear Medicine 51(3):340-6
Antoni Ribas, Matthias R. Benz, Martin S. Allen-Auerbach, Caius G. Radu, Bartosz Chmielowski, Narsis Attar, Elizabeth Seja, John L. Williams, John A. Glaspy, Jesus Gomez-Navarro, Timothy McCarthy, Johannes Czernin.

Stenciling Graphene, Carbon Nanotubes and Fullerenes Using Elastomeric Lift-Off Membranes
February 23 2010 - Advanced Materials 22(8): 897-901
Wassei JK, Tung VC, Jonas SJ, Cha K, Dunn BS, Yang Y, Kaner RB.

Metabolic control of G1-S transition: Cyclin E Degradation by p53-induced Activation of Ubiquitin Proteasome System
February 22 2010 - Journal of Cell Biology 188(4): 473-9
Mandal S, Freije WA, Guptan P, Banerjee U.

Identification of Differentially Expressed Proteins in Murine Embryonic and Postnatal Cortical Neural Progenitors
February 9 2010 - PLoS ONE 5(2):e9121
Shoemaker LD , Orozco NM, Geschwind DH, Whitelegge JP, Faull KF, Kornblum HI.

Immune Rejection in a Humanized Model of Murine Prostate Cancer
February 1 2010 - Anticancer Research 30 (2): 409-14
Dorthe Schaue, Richard C. Koya, Yu-Pei Liao, Antoni Ribas, William H. McBride.

Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjögren's syndrome-like exocrinopathy
February 2010 - Expermental Eye Research 90(2):223-37
Schenke-Layland K, Xie J, Magnusson M, Angelis E, Li X, Wu K, Reinhardt DP, Maclellan WR, Hamm-Alvarez SF.

A phase II clinical trial of nab-paclitaxel in previously-treated and chemotherapy naive patients with metastatic malignant melanoma
January 1 2010 - Cancer 116(1):155-63
Evan M. Hersh, Steven J. O'Day, Antoni Ribas, Wolfram E. Samlowski, Michael S. Gordon, Deganit Shechter, Alicia Clawson, Rene Gonzalez.

Accurate sodium bisulfite sequencing in plants
January 1 2010 - Epigenetics 5(1): 29-31
Ian R. Henderson, Simon R. Chan, Xiaofeng Cao, Lianna Johnson and Steven E. Jacobsen.