AMANDER CLARK, PhD
Assistant Professor, Department of Molecular, Cell, and Developmental Biology

Dr. Clark was recruited to UCLA, Department of Molecular Cell and Developmental Biology and the Broad Stem Cell Center at UCLA in the Summer of 2006.  Her training extended across two continents, namely Australian where she received a PhD in Anatomy and Cell Biology at the University of Melbourne, and the USA where she received postdoctoral training at Baylor College of Medicine in  mouse genetics, and University of California, San Francisco in human embryonic stem cell research. 

Dr. Clark's laboratory uses embryonic stem cells (ESCs) to understand the molecular events required for cell lineage differentiation and cancer progression. ESCs have the remarkable features of both self-renewal together with pluripotency. Therefore, by harnessing the power of these two properties, the lab is capable of generating numerous cell types derived from all embryonic lineages for molecular analysis. Her lab is specifically interested in analysis of the germ cell lineage. Germ cells have the critical role of ensuring that our genes are passed correctly from one generation to the next. Abnormal development of the germ cell lineage can result in infertility, germ cell tumor formation, diseases such as premature ovarian failure, or congenital abnormalities and birth defects. Dr. Clark's laboratory uses human ESCs together with systemic mouse modeling to understand the molecular events critical for normal human germ cell differentiation and function, and to explore key genetic pathways associated with germ cell tumor development.

Read more about Amander Clark::

• UCLA Access Page
• Jonsson Comprehensive Cancer Center Biography